Endocrine Abstracts

Background: Classical risk factors are not capable to explain all the cardiovascular events and new markers are being evaluated to predict events.Aims: We examined the effects of a single session of submaximal exercise (cardiopulmonary exercise cycle ergometer test) on atherogenic lipids in obese subjects focusing on inflammatory biomarker high-sensitivity C-reactive protein (hs-CRP), and oxidized low-density-lipoproteins (oxLDL) as a marker of oxidative...

The metabolic syndrome resembles Cushing’s syndrome in several clinical aspects. Main characteristic of both syndromes is obesity assessed by the body mass index (BMI) or waist circumference (WC).The aim of this study was to investigate cortisol dynamics in 20 healthy volunteers (BMI<27 kg/m2; 13 females, 7 males, age 42.1+12.39 years) and 20 obese patients (BMI≥27 kg/m2; 13 females, 7 males, age 49.25+1...

Background and aims: Plasminogen activator inhibitor -1 (PAI-1) increases in diabetes and this might contribute to decreased fibrinolisis and accelerated atherosclerosis. PAI-1 is also contributor to the development of acute myocardial infarction. Measurement of intimal medial thickening (IMT) is indicator of presence and extent of coronary artery disease. Aim of the study was to find association between PAI-1 marker of decreased fibrinolisis and atherosclerosis by measuring I...

Background/objectives: The aim of the study was to assess hypothalamic–pituitary–adrenal (HPA) axis in patients with chronic fatigue syndrome (CFS).Design and methods: Twenty-three consecutive patients who fulfilled centers for disease control (CDC) criteria for CFS and twenty healthy controls were included in the study. Low dose ACTH test (1mcg of synthetic adrenocorticotropic hormone Synacthen) and insulin tolerance test (ITT) were done and b...